Use nightly for 28 days on freshly cleansed skin. Start with Phase 1. Press cap to release Idebenone. Shake gently to mix. Remove cap and replace with dropper provided. Dispense a dropper-full of product onto your palm. Apply for full-face coverage, avoiding contact with eye area. Wait 20 minutes before applying any other products. Leave product on overnight. Use Phase 1 for 7 days, shaking lightly to mix before each application. At start of Week 2, change to Phase 2 and follow steps 1 – 4 every night through end of Phase 4.